Redefining Cancer Metabolism: How 7ACC2 Unlocks New Front...

2025-10-21

This thought-leadership article examines how the carboxycoumarin MCT1 inhibitor 7ACC2 is reshaping cancer metabolism research. It explores mechanistic insights into lactate transport inhibition, mitochondrial pyruvate blockade, and the immunometabolic reprogramming of the tumor microenvironment. Drawing on recent breakthroughs in TAM metabolic regulation, the article provides strategic guidance for translational researchers seeking to leverage 7ACC2 for next-generation cancer therapy discovery.